2012年在希腊库蚊中检测到西尼罗河病毒2型毒株。

Detection of West Nile virus lineage 2 in Culex mosquitoes, Greece, 2012.

作者信息

Papa Anna, Papadopoulou Elpida, Gavana Elpida, Kalaitzopoulou Stella, Mourelatos Spyros

机构信息

1 A' Department of Microbiology, Medical School, Aristotle University of Thessaloniki , Greece .

出版信息

Vector Borne Zoonotic Dis. 2013 Sep;13(9):682-4. doi: 10.1089/vbz.2012.1212. Epub 2013 May 22.

DOI:10.1089/vbz.2012.1212

PMID:23697769

Abstract

To gain insight into the strain(s) causing human cases of West Nile virus (WNV) infection in Greece in 2012, mosquitoes were collected and tested for probable WNV infection. WNV lineage 2 sequences were obtained from two of 14 Culex spp. pools collected in Xanthi Prefecture, and especially in the municipality with the highest incidence in Greece. As in the 2 previous years, the strain contains the H249P substitution in the NS3 protein. It seems that this specific strain is fully established in Greece and causes large-scale outbreaks. Thus, prevention and control measures have to be taken, while enhanced surveillance is needed.

摘要

为深入了解2012年在希腊导致人类西尼罗河病毒（WNV）感染病例的毒株，收集了蚊子并检测其是否可能感染WNV。从在克桑西州收集的14个库蚊属样本中的两个样本中获得了WNV 2型序列，特别是在希腊发病率最高的市。与前两年一样，该毒株在NS3蛋白中含有H249P替代。看来这种特定毒株已在希腊完全确立并导致大规模疫情爆发。因此，必须采取预防和控制措施，同时需要加强监测。