Department of Psychiatry, Kasturba Medical College, Manipal, Karnataka, India.
Am J Ther. 2014 Mar-Apr;21(2):e45-7. doi: 10.1097/MJT.0b013e31823581c8.
Bupropion is a norepinephrine dopamine-reuptake inhibitor that has been found to be effective in the treatment of nicotine dependence. Although well tolerated, seizures and psychosis have been described to occur with bupropion as severe adverse effects. We report the precipitation of acute psychosis with bupropion prescribed for smoking cessation in an elderly patient.
安非他酮是一种去甲肾上腺素和多巴胺再摄取抑制剂,已被证明对治疗尼古丁依赖有效。虽然安非他酮耐受性良好,但已描述其会出现严重不良反应,如癫痫发作和精神病。我们报告了一位老年患者因戒烟而开处方的安非他酮诱发急性精神病。