Lin C C, Meier M, Sorensen O, Sasi R, Tainaka T, Bleackley R C
Department of Pathology, University of Alberta, Edmonton, Canada.
Cytogenet Cell Genet. 1990;53(2-3):169-71. doi: 10.1159/000132921.
Two human serine protease genes have been cloned. One corresponds to CTLA1, the human equivalent of the mouse cytotoxic cell protease gene Ctla-1, and the other is novel. Both genes were localized to 14q11.2----q12 by in situ hybridization. This result confirms the assignment of human CTLA1 to 14q11.2----q12 and provides new mapping data for another human serine protease gene located in the same chromosome region.
已克隆出两个人类丝氨酸蛋白酶基因。其中一个对应于CTLA1，它相当于小鼠细胞毒性细胞蛋白酶基因Ctla-1的人类基因，另一个是新基因。通过原位杂交将这两个基因都定位到了14q11.2----q12。这一结果证实了人类CTLA1基因定位于14q11.2----q12，并为位于同一染色体区域的另一个人类丝氨酸蛋白酶基因提供了新的定位数据。
