American Hospital, Istanbul, Turkey.
Clin Nucl Med. 2013 Jul;38(7):566-8. doi: 10.1097/RLU.0b013e318292eeb4.
Intraglomerular metastasis is a very rare condition with an underlying cause that is not yet well understood. We present the 18F-FDG PET/CT images of histologically proven intraglomerular metastases from newly diagnosed malignant melanoma with positive sentinel lymph node metastases. During the initial diagnostic evaluation period, the patient also had a sudden increased serum creatinine level. FDG PET/CT demonstrated diffuse glomerular FDG uptake unlike typical physiologic pelvicaliceal activity. Renal biopsy revealed diffuse crescentic lesions containing metastatic melanoma cells.
球内转移是一种非常罕见的病症，其潜在病因尚不清楚。我们报告了一例经组织学证实的由新诊断的恶性黑色素瘤伴前哨淋巴结转移所致的球内转移的 18F-FDG PET/CT 图像。在初始诊断评估期间，患者的血清肌酐水平也突然升高。FDG PET/CT 显示弥漫性肾小球 FDG 摄取，与典型的肾盂肾盏生理性活动不同。肾活检显示弥漫性新月体病变，其中含有转移性黑色素瘤细胞。
