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瑞典矽肺病陶瓷工人中的肺癌发病率。

Lung cancer incidence among Swedish ceramic workers with silicosis.

作者信息

Tornling G, Hogstedt C, Westerholm P

机构信息

Department of Occupational Medicine, Karolinska Hospital, Stockholm, Sweden.

出版信息

IARC Sci Publ. 1990(97):113-9.

PMID:2370098
Abstract

The incidence of lung cancer among 280 silicotic men working in the ceramics industry and notified to the Swedish Silicosis Registry has been investigated. During the study period 1958-83, the risk of lung cancer (nine cases) was double that expected based on national rates. There was no increased incidence of cancer at any other site. The results are in agreement with those of both animal and epidemiological studies of quartz exposure and point to an increased risk of lung cancer, especially among silicotics. Various possible explanations of this increased risk are discussed, but further studies are required.

摘要

对280名在陶瓷行业工作并已通报给瑞典矽肺病登记处的矽肺男性患者的肺癌发病率进行了调查。在1958年至1983年的研究期间,肺癌风险(9例)是根据全国发病率预期的两倍。其他任何部位的癌症发病率均未增加。这些结果与石英暴露的动物研究和流行病学研究结果一致,并表明肺癌风险增加,尤其是在矽肺患者中。讨论了这种风险增加的各种可能解释,但仍需要进一步研究。

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