Department of Radiology, Santa Clara Valley Medical Center, 751 S Bascom Ave, San Jose, CA 95128, USA.
AJR Am J Roentgenol. 2013 Jun;200(6):1334-46. doi: 10.2214/AJR.12.9264.
The purpose of this study was to evaluate the prevalence and significance of concurrent coccidioidal brain and intraspinal disease.
We conducted a retrospective imaging review of 23 patients with proven coccidioidal CNS meningitis.
All patients had intracranial abnormalities, and 86% (19/22) who underwent spinal imaging had signs of intraspinal disease, including leptomeningeal enhancement (84%), arachnoiditis (63%), and cord signal abnormalities (37%); seven of 15 patients (47%) who underwent myelography had complete spinal blocks.
The high prevalence of concurrent brain and intraspinal coccidioidomycosis supports a low threshold for spinal imaging.
本研究旨在评估并发球孢子菌性脑和脊髓疾病的患病率和意义。
我们对 23 例确诊为中枢神经系统球孢子菌病脑膜炎的患者进行了回顾性影像学检查。
所有患者均有颅内异常，22 例行脊髓影像学检查的患者中有 86%（19/22）存在脊髓疾病的迹象，包括脑膜强化（84%）、蛛网膜炎（63%）和脊髓信号异常（37%）；15 例行脊髓造影的患者中有 7 例（47%）存在完全性脊髓阻塞。
脑和脊髓球孢子菌病同时发生的高患病率支持对脊髓成像的低阈值。
