中枢神经系统球孢子菌病的影像学谱：同时存在脑部和脊髓疾病的患病率和意义。
Imaging spectrum of CNS coccidioidomycosis: prevalence and significance of concurrent brain and spinal disease.
机构信息
Department of Radiology, Santa Clara Valley Medical Center, 751 S Bascom Ave, San Jose, CA 95128, USA.
出版信息
AJR Am J Roentgenol. 2013 Jun;200(6):1334-46. doi: 10.2214/AJR.12.9264.
OBJECTIVE
The purpose of this study was to evaluate the prevalence and significance of concurrent coccidioidal brain and intraspinal disease.
MATERIALS AND METHODS
We conducted a retrospective imaging review of 23 patients with proven coccidioidal CNS meningitis.
RESULTS
All patients had intracranial abnormalities, and 86% (19/22) who underwent spinal imaging had signs of intraspinal disease, including leptomeningeal enhancement (84%), arachnoiditis (63%), and cord signal abnormalities (37%); seven of 15 patients (47%) who underwent myelography had complete spinal blocks.
CONCLUSION
The high prevalence of concurrent brain and intraspinal coccidioidomycosis supports a low threshold for spinal imaging.
目的
本研究旨在评估并发球孢子菌性脑和脊髓疾病的患病率和意义。
材料和方法
我们对 23 例确诊为中枢神经系统球孢子菌病脑膜炎的患者进行了回顾性影像学检查。
结果
所有患者均有颅内异常，22 例行脊髓影像学检查的患者中有 86%（19/22）存在脊髓疾病的迹象，包括脑膜强化（84%）、蛛网膜炎（63%）和脊髓信号异常（37%）；15 例行脊髓造影的患者中有 7 例（47%）存在完全性脊髓阻塞。
结论
脑和脊髓球孢子菌病同时发生的高患病率支持对脊髓成像的低阈值。
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