Bozic Kevin J, Ward Derek T, Lau Edmund C, Chan Vanessa, Wetters Nathan G, Naziri Qais, Odum Susan, Fehring Thomas K, Mont Michael A, Gioe Terence J, Della Valle Craig J
Department of Orthopaedic Surgery, University of California, San Francisco, San Francisco, California; University of California, San Francisco, San Francisco, Philip R. Lee Institute for Health Policy Studies, San Francisco, California.
J Arthroplasty. 2014 Jan;29(1):154-6. doi: 10.1016/j.arth.2013.04.015. Epub 2013 May 20.
The purpose of this study was to identify the specific comorbidities and demographic factors that are independently associated with an increased risk of periprosthetic joint infection (PJI) in total hip arthroplasty (THA) patients. A case-control study design was used to compare 88 patients who underwent unilateral primary THA and developed PJI with 499 unilateral primary THA patients who did not develop PJI. The impact of 18 comorbid conditions and other demographic factors on PJI was examined. Depression, obesity, cardiac arrhythmia, and male gender were found to be independently associated with an increased risk of PJI in THA patients. This information is important to consider when counseling patients on the risks associated with elective THA, and for risk-adjusting publicly reported THA outcomes.
本研究的目的是确定在全髋关节置换术（THA）患者中，与假体周围关节感染（PJI）风险增加独立相关的特定合并症和人口统计学因素。采用病例对照研究设计，比较了88例接受单侧初次THA并发生PJI的患者与499例未发生PJI的单侧初次THA患者。研究了18种合并症和其他人口统计学因素对PJI的影响。发现抑郁症、肥胖、心律失常和男性性别与THA患者发生PJI的风险增加独立相关。在就择期THA相关风险向患者提供咨询时，以及在对公开报告的THA结果进行风险调整时，考虑这些信息很重要。
