Department of Obstetrics and Gynecology, Peking Union Medical College Hospital, Beijing, PR China.
Am J Obstet Gynecol. 2013 Sep;209(3):241.e1-9. doi: 10.1016/j.ajog.2013.05.032. Epub 2013 May 20.
Clinicopathological characteristics and possible prognostic factors among women with endometrioid epithelial ovarian cancer (EEOC) with or without concurrent endometriosis were investigated.
A search of medical charts at Peking Union Medical College Hospital from 2000 through 2012 identified patients with EEOC with or without endometriosis.
Of 188 patients with EEOC, concurrent endometriosis was identified in 32 (17.0%). Patients with concurrent endometriosis were approximately 5 years younger, more likely to be premenopausal, more likely to have an early stage of EEOC, and less likely to have high-grade tumors compared to those without endometriosis. The univariate analysis showed that concurrent endometriosis was a significant prognostic factor for disease-free survival, but this association did not remain in the multivariate analysis.
Women with EEOC and concurrent endometriosis showed distinct characteristics and had longer disease-free survival when compared to those without endometriosis.
研究合并或不合并子宫内膜异位症的子宫内膜样卵巢上皮癌(EEOC)患者的临床病理特征及可能的预后因素。
对北京协和医学院医院 2000 年至 2012 年的病历进行检索,以确定合并或不合并子宫内膜异位症的 EEOC 患者。
在 188 例 EEOC 患者中,有 32 例(17.0%)合并子宫内膜异位症。与无子宫内膜异位症的患者相比,合并子宫内膜异位症的患者年龄约小 5 岁,更有可能处于绝经前状态,更有可能处于 EEOC 的早期阶段,且高级别肿瘤的发生率较低。单因素分析显示,合并子宫内膜异位症是无病生存期的显著预后因素,但这一关联在多因素分析中并不存在。
与无子宫内膜异位症的 EEOC 患者相比,合并子宫内膜异位症的 EEOC 患者表现出明显的特征,且无病生存期更长。