Stylianos S, Chen M H, Treat M R, LoGerfo P, Rose E A
Division of Cardiothoracic Surgery, Columbia University College of Physicians and Surgeons, New York, NY.
J Cardiovasc Surg (Torino). 1990 May-Jun;31(3):315-7.
Lower gastrointestinal hemorrhage in immunosuppressed transplant recipients is associated with significant morbidity and mortality. This hemorrhage is often massive and frequently due to ulceration of the colon by opportunistic organisms requiring early diagnosis and resection. We report a heart transplant recipient with massive rectal bleeding from an unsuspected lymphoproliferative lesion of the sigmoid colon treated successfully with prompt surgical resection and reduction of immunosuppression. Although lymphoproliferative lesions are common in transplant recipients, particularly in those immunosuppressed with cyclosporine, we believe massive rectal bleeding to be a unique presentation of such a lesion.
免疫抑制的移植受者发生下消化道出血与显著的发病率和死亡率相关。这种出血通常量大，且常因机会性生物体导致结肠溃疡所致，需要早期诊断和切除。我们报告一例心脏移植受者，其因乙状结肠未被怀疑的淋巴增殖性病变出现大量直肠出血，经及时手术切除和减少免疫抑制后成功治愈。尽管淋巴增殖性病变在移植受者中很常见，尤其是那些接受环孢素免疫抑制治疗的患者，但我们认为大量直肠出血是此类病变的一种独特表现。
