Leucht S, Heres S, Kissling W, Davis J M
Department of Psychiatry and Psychotherapy, Technische Universität München, Klinikum rechts der Isar, München, Germany.
Fortschr Neurol Psychiatr. 2013 May;81(5):e1-13. doi: 10.1055/s-0033-1335405. Epub 2013 May 23.
We present the pharmacological treatment of schizophrenia based on a simple algorithm that starts with the most important decisions starting from the choice of an antipsychotic drug for an acutely ill patient and ends with maintenance treatment. It represents experts opinions, a formal guideline development process was not followed. Concerning acute treatment we present recommendations for the choice of drug in acutely patients, the treatment of agitated patients, persistent depression, negative symptoms and treatment resistance. Concerning maintenance treatment with antipsychotics we discuss indication, choice of drug, continuous versus intermittent treatment, duration of relapse prevention and dose.
我们基于一个简单的算法介绍精神分裂症的药物治疗，该算法从最重要的决策开始，从为急性病患者选择抗精神病药物入手，直至维持治疗结束。它代表了专家意见，未遵循正式的指南制定流程。关于急性治疗，我们给出了针对急性病患者药物选择、激越患者治疗、持续性抑郁、阴性症状及治疗抵抗的建议。关于抗精神病药物的维持治疗，我们讨论了适应证、药物选择、持续治疗与间歇治疗、预防复发的时长及剂量。
