University of Arkansas for Medical Sciences, AR, USA.
Blood. 2013 May 23;121(21):4251-2. doi: 10.1182/blood-2013-04-494856.
In this issue of Blood, Yuan et al provide evidence that processing of the first intronic sequence within the von Willebrand factor (vWF) gene facilitates expression by endothelial cells regardless of the source of the intron, while intron processing is irrelevant for vWF expression by megakaryocytes.(1)
在本期《Blood》中，袁等人提供了证据，表明无论内含子的来源如何，血管性血友病因子 (vWF) 基因第一内含子序列的加工都能促进内皮细胞的表达，而内含子的加工对于巨核细胞中 vWF 的表达则无关紧要。(1)
