James P L, O'Regan M B, Speight P M
Department of Oral and Maxillo-Facial Surgery, London Hospital, Whitechapel.
J Laryngol Otol. 1990 Apr;104(4):335-40. doi: 10.1017/s0022215100112642.
The case of an osteosarcoma arising in the mandible of a six-year-old child is presented. It was originally misdiagnosed as a desmoplastic fibroma, and after initial curettage continued to grow for twelve years. The differential diagnosis is presented and details of the surgical access and difficulties encountered in the surgical removal of this very large tumour are described. The relationship between pre-existing disease and osteosarcoma of the mandible is discussed, and the difficulties experienced in distinguishing between the fibro-osseous lesions and osteosarcoma of the mandible are highlighted. The case is presented as a well-differentiated, intra-osseous osteosarcoma with subsequent transformation into a high-grade, conventional osteosarcoma.
本文介绍了一例发生在一名六岁儿童下颌骨的骨肉瘤病例。该病例最初被误诊为促纤维增生性纤维瘤，在初次刮除术后持续生长了十二年。文中给出了鉴别诊断，并描述了手术入路以及切除这一巨大肿瘤时遇到的困难。讨论了既往疾病与下颌骨肉瘤之间的关系，并强调了区分下颌骨纤维骨性病变和骨肉瘤所面临的困难。该病例表现为高分化的骨内骨肉瘤，随后转变为高级别传统骨肉瘤。
