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多囊卵巢综合征妇女的排卵诱导。

Ovulation induction in women with polycystic ovary syndrome.

机构信息

Department of Obstetrics and Gynecology, Pennsylvania State University College of Medicine, Hershey, PA, USA.

出版信息

Steroids. 2013 Aug;78(8):767-72. doi: 10.1016/j.steroids.2013.05.005. Epub 2013 May 21.

Abstract

Polycystic ovary syndrome (PCOS) is the most common cause of anovulatory infertility. There are multiple ways to induce ovulation in PCOS patients, which will eventually provide a successful live birth. Each of these treatments varies in aggressiveness and effectiveness. Ranging from lifestyle modifications, through insulin-sensitizing agents, selective estrogen receptor modulators, aromatase inhibitors, gonadotropins, to laparoscopic ovarian drilling and assisted reproductive techniques, each method achieves ovulation induction through different mechanisms of action. This review provides a description and specific characteristics of the different methods used for ovulation induction which can help to design a personalized approach to each PCOS patient, and a general stepwise approach to ovulation induction in these patients.

摘要

多囊卵巢综合征(PCOS)是排卵障碍性不孕的最常见原因。有多种方法可诱导 PCOS 患者排卵,最终可实现成功活产。这些治疗方法在侵袭性和有效性方面存在差异。从生活方式的改变,到胰岛素增敏剂、选择性雌激素受体调节剂、芳香化酶抑制剂、促性腺激素,再到腹腔镜卵巢打孔术和辅助生殖技术,每种方法通过不同的作用机制实现排卵诱导。本文综述了不同的排卵诱导方法,并详细描述了它们各自的特点,有助于为每位 PCOS 患者设计个性化的方法,以及为这些患者制定一般性的排卵诱导步骤。

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