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食管下括约肌功能与体力活动水平之间的关系。

Associations between the lower esophageal sphincter function and the level of physical activity.

机构信息

Department of Gastroenterology and Hepatology Wroclaw Medical University, Poland.

出版信息

Adv Clin Exp Med. 2013 Mar-Apr;22(2):185-91.

Abstract

BACKGROUND

Gastroesophageal reflux disease (GERD) is a very frequent and multifactorial disease. It has been found that GERD is associated with obesity, smoking, esophagitis, diet and lifestyle. Physical activity is among the factors involved in the occurrence of GERD.

OBJECTIVES

The aim of the study was to evaluate the associations between the different parameters of lower esophageal pressure (LES) and the level of everyday physical activity in patients with GERD.

MATERIAL AND METHODS

The authors examined 100 consecutive patients who underwent manometry and pH-metry because of symptoms suggesting GERD. Physical activity was assessed by means of the International Physical Activity Questionnaire (IPAQ). In accordance with IPAQ categorical scoring, the authors divided the studied subjects into 3 groups according to their level of physical activity. The investigation comprised 59 men and 41 women, with the mean age 49 ± 14 years.

RESULTS

The authors analyzed the relationships between the LES parameters (pressure, total LES length and HPZ length) and physical activity. The authors did not find any significant correlations between the studied parameters and the amount of physical activity. The authors also did not observe any association between the LES pressure and the level of physical activity. The subgroups distinguished on the basis of LESP did not differ as to the amount of everyday physical activity as well.

CONCLUSIONS

Although most data indicates that intense exercise exacerbates GERD symptoms, the authors did not find any associations between LES parameters and physical activity. In view of the present results maintaining the recommended level of everyday physical activity does not interfere with the mechanisms of GERD.

摘要

背景

胃食管反流病(GERD)是一种非常常见且多因素的疾病。已经发现 GERD 与肥胖、吸烟、食管炎、饮食和生活方式有关。体力活动是 GERD 发生的相关因素之一。

目的

本研究旨在评估 GERD 患者下食管压力(LES)的不同参数与日常体力活动水平之间的关系。

材料和方法

作者检查了 100 名连续因 GERD 症状而接受测压和 pH 监测的患者。通过国际体力活动问卷(IPAQ)评估体力活动。根据 IPAQ 分类评分,作者根据体力活动水平将研究对象分为 3 组。研究对象包括 59 名男性和 41 名女性,平均年龄为 49 ± 14 岁。

结果

作者分析了 LES 参数(压力、总 LES 长度和 HPZ 长度)与体力活动之间的关系。作者未发现研究参数与体力活动量之间存在任何显著相关性。作者也未观察到 LES 压力与体力活动水平之间存在任何关联。基于 LESP 区分的亚组在日常体力活动量方面也没有差异。

结论

尽管大多数数据表明剧烈运动加剧 GERD 症状,但作者未发现 LES 参数与体力活动之间存在任何关联。鉴于目前的结果,保持推荐的日常体力活动水平不会干扰 GERD 的发生机制。

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