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干燥综合征患者发生致命性母细胞样变异型套细胞淋巴瘤

Fatal Blastoid Variant Mantle Cell Lymphoma in a Patient with Sjögren's Syndrome.

作者信息

Bonilla-Abadía Fabio, Pérez Manuel A, Muñoz-Buitrón Evelyn, Rosales Joaquín D, Cañas Carlos A, Tobón Gabriel J

机构信息

Rheumatology Unit, Fundación Valle del Lili, ICESI University, Cali, Colombia.

出版信息

Case Rep Rheumatol. 2013;2013:831708. doi: 10.1155/2013/831708. Epub 2013 Apr 23.

DOI:10.1155/2013/831708
PMID:23710406
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3655507/
Abstract

Primary Sjögren's syndrome (pSS) is an autoimmune disorder of the exocrine glands presenting with progressive ocular and oral dryness, parotid gland enlargement, and often with extraglandular manifestations. In this group of patients the risk of development of non-Hodgkin's lymphoma is 16-fold compared to healthy population, mainly of the MALT lymphoma type. This case reports a 52-year-old woman with pSS developing a progressively growing mass at face and neck compatible with blastoid variant mantle cell lymphoma and a fatal outcome.

摘要

原发性干燥综合征（pSS）是一种外分泌腺的自身免疫性疾病，表现为进行性眼干和口干、腮腺肿大，且常伴有腺体外表现。在这组患者中，非霍奇金淋巴瘤的发生风险是健康人群的16倍，主要为黏膜相关淋巴组织（MALT）淋巴瘤类型。本病例报告了一名52岁患有原发性干燥综合征的女性，其面部和颈部出现逐渐增大的肿块，符合母细胞样变异型套细胞淋巴瘤，最终导致死亡。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6568/3655507/65a37908f137/CRIM.RHEUMATOLOGY2013-831708.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6568/3655507/2ceb109e84eb/CRIM.RHEUMATOLOGY2013-831708.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6568/3655507/c48522c8fc39/CRIM.RHEUMATOLOGY2013-831708.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6568/3655507/65a37908f137/CRIM.RHEUMATOLOGY2013-831708.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6568/3655507/2ceb109e84eb/CRIM.RHEUMATOLOGY2013-831708.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6568/3655507/c48522c8fc39/CRIM.RHEUMATOLOGY2013-831708.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6568/3655507/65a37908f137/CRIM.RHEUMATOLOGY2013-831708.003.jpg

相似文献

1
Fatal Blastoid Variant Mantle Cell Lymphoma in a Patient with Sjögren's Syndrome.干燥综合征患者发生致命性母细胞样变异型套细胞淋巴瘤
Case Rep Rheumatol. 2013;2013:831708. doi: 10.1155/2013/831708. Epub 2013 Apr 23.
2
Primary Sjögren's syndrome complicated with development of non-Hodgkin's lymphoma - a case report and literature review.原发性干燥综合征合并非霍奇金淋巴瘤的发生——一例报告及文献复习
J BUON. 2002 Jul-Sep;7(3):277-80.
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[The role of parotid gland biopsy in early detection of lymphoma in primary Sjogren's syndrome].[腮腺活检在原发性干燥综合征淋巴瘤早期检测中的作用]
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Germinal centres in diagnostic labial gland biopsies of patients with primary Sjögren's syndrome are not predictive for parotid MALT lymphoma development.原发性干燥综合征患者唇腺活检中的生发中心并不能预测腮腺 MALT 淋巴瘤的发生。
Ann Rheum Dis. 2017 Oct;76(10):1781-1784. doi: 10.1136/annrheumdis-2017-211290. Epub 2017 Jul 14.
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MALT Lymphoma of Minor Salivary Glands in a Sjögren's Syndrome Patient: a Case Report and Review of Literature.干燥综合征患者小唾液腺MALT淋巴瘤：一例报告并文献复习
J Oral Maxillofac Res. 2017 Mar 31;8(1):e5. doi: 10.5037/jomr.2017.8105. eCollection 2017 Jan-Mar.
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MALT Lymphoma of the Tongue in a Patient with Sjögren's Syndrome: A Case Report and Literature Review.干燥综合征患者舌部黏膜相关淋巴组织淋巴瘤：一例报告及文献复习
Diagnostics (Basel). 2021 Sep 19;11(9):1715. doi: 10.3390/diagnostics11091715.
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Sjögren's syndrome in patients with newly diagnosed untreated non-Hodgkin's lymphoma.新诊断未治疗的非霍奇金淋巴瘤患者中的干燥综合征
Rev Rhum Engl Ed. 1997 May;64(5):287-92.
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Primary Sjögren's syndrome initially presenting as submandibular mucosa-associated lymphoid tissue lymphoma: A case report.原发性干燥综合征初发表现为下颌下黏膜相关淋巴组织淋巴瘤：一例报告
Oncol Lett. 2016 Feb;11(2):921-924. doi: 10.3892/ol.2015.3980. Epub 2015 Nov 30.
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Submandibular gland MALT lymphoma associated with Sjögren's syndrome: case report.与干燥综合征相关的下颌下腺黏膜相关淋巴组织淋巴瘤：病例报告
J Oral Maxillofac Surg. 2011 Nov;69(11):2924-9. doi: 10.1016/j.joms.2011.02.033. Epub 2011 May 6.

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Malignant lymphomas of the salivary glands. Review of the literature and report of 33 new cases, including four cases associated with the lymphoepithelial lesion.涎腺恶性淋巴瘤。文献综述及33例新病例报告，其中包括4例与淋巴上皮病变相关的病例。
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