Mathiesen Birgit B, Simonsen Erik, Soegaard Ulf, Kvist Kajsa
a Department of Psychology , University of Copenhagen , Copenhagen , Denmark.
Cogn Neuropsychiatry. 2014;19(1):1-16. doi: 10.1080/13546805.2013.776494. Epub 2013 May 28.
Previous research has shown that brain injury patients with Organic Personality Disorder (OPD) may display "borderline" traits due to prefrontal damage, and their personality structure may be unstable and close to a borderline personality organisation. They may have few general neuropsychological dysfunctions but specific executive deficits. Similar deficits have been found in patients with Borderline Personality Disorder (BPD). The objective of this study was to identify differences and similarities between the neuropsychological and personality profiles of BPD and OPD patients.
Twenty BPD patients and 24 OPD patients were assessed with the Structured Clinical Interview for DSM-IV Axis II Disorders (SCID-II), the Karolinska Psychodynamic Profile (KAPP), and a comprehensive neuropsychological test battery.
Very few neuropsychological differences were found between the two patient groups. However, the verbal fluency, verbal intelligence, verbal memory, and immediate auditory memory/attention of the BPD patients were significantly poorer than the OPD patients'. The KAPP profiles of the BPD patients showed significantly poorer functioning in three areas: frustration tolerance, the body as a factor of self-esteem, and overall personality organisation.
These results support our clinical experience and expectations concerning the severity of symptoms of both patient groups. We suggest considering in depth assessments of both neuropsychological and personality-related problems for each of these patients in order to inform treatment.
先前的研究表明,患有器质性人格障碍(OPD)的脑损伤患者可能由于前额叶损伤而表现出“边缘性”特质,其人格结构可能不稳定且接近边缘性人格组织。他们可能几乎没有一般的神经心理功能障碍,但存在特定的执行功能缺陷。在边缘性人格障碍(BPD)患者中也发现了类似的缺陷。本研究的目的是确定BPD患者和OPD患者在神经心理和人格特征方面的差异与相似之处。
对20名BPD患者和24名OPD患者进行了《精神疾病诊断与统计手册》第四版轴II障碍的结构化临床访谈(SCID-II)、卡罗林斯卡心理动力剖面图(KAPP)以及一套全面的神经心理测试。
在两组患者之间发现的神经心理差异极少。然而,BPD患者的言语流畅性、言语智力、言语记忆和即时听觉记忆/注意力明显比OPD患者差。BPD患者的KAPP剖面图在三个方面显示出明显较差的功能:挫折耐受力、作为自尊因素的身体以及整体人格组织。
这些结果支持了我们对两组患者症状严重程度方面的临床经验和预期。我们建议对这些患者中的每一位进行神经心理和人格相关问题的深入评估,以便为治疗提供依据。