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乳头状输卵管增生相关的卵巢非典型性增生性浆液性肿瘤和低级别浆液性癌的突变分析。

Mutation analysis of papillary tubal hyperplasia associated with ovarian atypical proliferative serous tumor and low-grade serous carcinoma.

机构信息

Department of Anatomic Pathology, Far Eastern Memorial Hospital, Taipei, Taiwan.

出版信息

Am J Obstet Gynecol. 2013 Aug;209(2):e6-8. doi: 10.1016/j.ajog.2013.05.044. Epub 2013 May 24.

DOI:10.1016/j.ajog.2013.05.044
PMID:23711666
Abstract

We present a patient with ovarian atypical proliferative serous tumor and low-grade serous carcinoma, related to KRAS mutation. Bilateral fallopian tubes had papillary tubal hyperplasia, providing additional evidence that it is the putative precursor of low-grade serous tumors. Mutation analysis of papillary tubal hyperplasia has not been done in previous literature.

摘要

我们现介绍一例卵巢非典型增生性浆液性肿瘤伴低级别浆液性癌患者，与 KRAS 突变相关。双侧输卵管均存在乳头状输卵管增生，为低级别浆液性肿瘤的潜在前驱病变提供了更多证据。之前的文献中并未报道过对乳头状输卵管增生进行突变分析。

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