Lovald Scott T, Ong Kevin L, Lau Edmund C, Schmier Jordana K, Bozic Kevin J, Kurtz Steve M
Exponent, Inc., Menlo Park, California.
J Arthroplasty. 2014 Jan;29(1):242-6. doi: 10.1016/j.arth.2013.04.031. Epub 2013 May 24.
The purpose of this study is to compare the differences in downstream cost and health outcomes between Medicare hip OA patients who undergo total hip arthroplasty (THA) and those who do not. All OA patients in the Medicare 5% sample (1998-2009) were separated into non-THA and THA groups. Differences in costs and risk ratios for mortality and new disease diagnoses were adjusted using logistic regression for age, sex, race, socioeconomic status, region, and Charlson score. Mortality, heart failure, depression, and diabetes were all reduced in the THA group, though there was an increased risk for atherosclerosis in the short term. The potential for selection bias was investigated with two separate propensity score analyses. This study demonstrates the potential benefit of THA in reducing mortality and improving aspects of overall health in OA patients.
本研究的目的是比较接受全髋关节置换术(THA)的医疗保险髋关节骨关节炎(OA)患者与未接受该手术的患者在下游成本和健康结局方面的差异。医疗保险5%样本(1998 - 2009年)中的所有OA患者被分为非THA组和THA组。使用逻辑回归对年龄、性别、种族、社会经济地位、地区和查尔森评分进行调整,以分析成本以及死亡率和新疾病诊断的风险比差异。THA组的死亡率、心力衰竭、抑郁症和糖尿病发生率均有所降低,不过短期内动脉粥样硬化风险有所增加。通过两项独立的倾向评分分析对选择偏倚的可能性进行了调查。本研究证明了THA在降低OA患者死亡率和改善整体健康状况方面的潜在益处。