Craig A, Taberner D A, Fisher A H, Foster D N, Mitra J
Department of Haematology, Withington Hospital, Manchester, UK.
Postgrad Med J. 1990 May;66(775):389-91. doi: 10.1136/pgmj.66.775.389.
A kindred with Type I protein S deficiency is described in which the index case developed skin necrosis during induction of oral anticoagulant therapy for deep venous thrombosis. Two other family members with protein S deficiency have been detected, and demonstrate the clinical variability of this condition.
本文描述了一个患有I型蛋白S缺乏症的家族,其中索引病例在因深静脉血栓形成进行口服抗凝治疗诱导期间发生了皮肤坏死。另外两名患有蛋白S缺乏症的家族成员已被检测出,这表明了该病症的临床变异性。