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腹主动脉瘤破裂手术修复后48小时内进行常规柔性乙状结肠镜检查的价值。

The value of routine flexible sigmoidoscopy within 48 hours after surgical repair of ruptured abdominal aortic aneurysms.

作者信息

Tøttrup Mikkel, Fedder Anette M, Jensen Reinhold H, Tøttrup Anders, Laustsen Jesper

机构信息

Department of Surgery P, Aarhus University Hospital, Aarhus, Denmark.

出版信息

Ann Vasc Surg. 2013 Aug;27(6):714-8. doi: 10.1016/j.avsg.2012.07.030. Epub 2013 May 24.

Abstract

BACKGROUND

Left-sided colonic and rectal ischemia is commonly seen after surgery for ruptured abdominal aortic aneurysms (rAAAs) and is associated with increased mortality. Earlier studies have shown that flexible sigmoidoscopy (FS) may detect ischemia when performed postoperatively, and suggestions have been made that patients can be selected for FS based on clinical and biochemical parameters. We sought to perform FS in all patients surviving the first 24 hours after surgery for rAAA and to compare the findings of FS to clinical and biochemical parameters.

METHODS

All patients undergoing emergency surgery for rAAA and surviving the first 24 hours underwent FS to assess any degree of ischemia.

RESULTS

During the study period, 41 patients survived the first 24 hours after surgery. In 9 (22%) patients, some degree of colonic ischemia was found. Segmental necrosis was only shown in 5% at first FS. Patients with ischemia received more blood transfusions intraoperatively than those with normal findings at FS. They also had longer periods with mean blood pressure <60 mm Hg postoperatively, and lower arterial pH on the first postoperative day. Blood lactate levels did not differ between the groups. None of the parameters were sufficiently discriminative to be used for distinguishing between patients with and without ischemia.

CONCLUSIONS

Severe colonic ischemia was less common than previously reported. All cases of colonic ischemia were identified by early FS, but none of the clinical and biochemical parameters were sufficiently reliable to distinguish between patients with and without ischemia. It is suggested that all patients initially surviving surgery for rAAA should be offered FS to screen for colonic ischemia.

摘要

背景

腹主动脉瘤破裂(rAAA)手术后常见左侧结肠和直肠缺血,且与死亡率增加相关。早期研究表明,术后进行乙状结肠镜检查(FS)可能检测到缺血情况,并且有人提出可根据临床和生化参数选择患者进行FS检查。我们试图对所有在rAAA手术后存活24小时的患者进行FS检查,并将FS检查结果与临床和生化参数进行比较。

方法

所有接受rAAA急诊手术且存活24小时的患者均接受FS检查以评估缺血程度。

结果

在研究期间,41例患者在手术后存活了24小时。9例(22%)患者发现有一定程度的结肠缺血。首次FS检查时仅5%的患者出现节段性坏死。缺血患者术中输血比FS检查结果正常的患者更多。他们术后平均血压<60 mmHg的时间也更长,术后第一天动脉pH值更低。两组之间血乳酸水平无差异。没有一个参数具有足够的鉴别力来区分有无缺血的患者。

结论

严重结肠缺血比先前报道的少见。所有结肠缺血病例均通过早期FS检查得以识别,但没有一个临床和生化参数足够可靠来区分有无缺血的患者。建议对所有最初在rAAA手术后存活的患者进行FS检查以筛查结肠缺血。

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