Fan Yong-ping, Hu Rui, Bao Xian-hui, Wu Wei
Department of Traditional Chinese Medicine, Beijing Tiantan Hospital Affiliated to Capital Medical University, Beijing 100050, China.
Zhongguo Zhong Xi Yi Jie He Za Zhi. 2013 Mar;33(3):322-5.
To explore the clinical features of neuromyelitis optica (NMO) patients, and to study the distribution of Chinese medical syndrome types and the pathogenesis of NMO.
The clinical features, figures of tongue and pulse, Chinese medical syndromes were comprehensively analyzed in 63 NMO patients using statistical methods for clinical data.
The age ratio of male to female in 63 NMO patients was 1: 6.88. Their average age of first onset was 31.67 +/- 12.44 years old, and 28. 57% of patients had obvious inducing factor. Urgent onset with relieved recurrence were often seen, with the average recurrence times of 4.60. Most patients complained about sensation disorders, vision disorders, and movement disorders as their first attack and visit. The Chinese medical syndrome types included Gan-Shen yin deficiency syndrome and phlegm-heat collateral stagnation syndrome, mainly involved Gan and Shen. Gan-Shen yin deficiency, sputum, blood stasis, and heat were most often seen syndrome elements.
Gan-Shen yin deficiency was dominated in the deficiency in origin of NMO. Phlegm, blood stasis, mingled heat were main dominant evils. Of them, the pathogenesis of Gan-Shen yin deficiency and phlegm-heat collateral stagnation had universality and representativeness, which could be verified from patients' tongue picture and pulse picture.
探讨视神经脊髓炎（NMO）患者的临床特征，研究NMO的中医证型分布规律及发病机制。
采用统计学方法对63例NMO患者的临床资料进行综合分析，包括临床特征、舌象、脉象及中医证候。
63例NMO患者男女比例为1∶6.88，首次发病平均年龄为（31.67±12.44）岁，28.57%的患者有明显诱因。常急发缓复，平均复发次数为4.60次。多数患者首发症状及就诊原因以感觉障碍、视力障碍、运动障碍为主。中医证型包括肝肾阴虚证和痰热阻络证，病位主要在肝、肾。肝肾阴虚、痰、瘀、热为常见证素。
NMO本虚以肝肾阴虚为主，标实以痰、瘀、热为主。其中肝肾阴虚与痰热阻络的发病机制具有普遍性和代表性，可从患者的舌象、脉象中得到印证。
