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[大鼠淋巴系统组织和红细胞膜中辐射诱导的甾醇和角鲨烯含量变化特征]

[Characteristics of the radiation-induced changes in the content of sterols and squalene in the lymphoid system tissues and erythrocyte membranes of rats].

作者信息

Palamarchuk V I

出版信息

Radiobiologiia. 1990 May-Jun;30(3):321-7.

PMID:2371389
Abstract

Ionizing radiation causes considerable changes in the content of sterols and squalene in the lymphoid system tissues and erythrocyte membranes which is in accordance with the concept of high radiosensitivity of haemopoietic tissue. The processes of cholesterol conversion to its oxy-derivatives are increased under the effect of radiation. The content of some lipid components in the lymphoid system tissues and erythrocyte membranes is changed depending on the dose and time after irradiation. There is a relationship between the changes in the sterol composition and in the properties of erythrocyte membranes.

摘要

电离辐射会导致淋巴系统组织和红细胞膜中甾醇和角鲨烯含量发生显著变化,这与造血组织具有高放射敏感性的概念相符。在辐射作用下,胆固醇转化为其氧化衍生物的过程会增强。淋巴系统组织和红细胞膜中某些脂质成分的含量会根据辐射后的剂量和时间而发生变化。甾醇组成的变化与红细胞膜的特性之间存在关联。

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