[分裂细胞的间期死亡。间期死亡与细胞能量需求的关系]
[The interphase death of dividing cells. The relation of interphase death to cell energy requirements].
作者信息
Degtiareva O V, Korystov Iu N, Kublik L N, Veksler A M, Dobrovinskaia O R, Eĭdus L Kh
出版信息
Radiobiologiia. 1990 May-Jun;30(3):407-10.
PMID:2371401
Abstract
In experiments with irradiated cells of Chinese hamster and Ehrlich ascites tumor a study was made of the influence of energy provision on their interphase death rate. The presence of the uncoupler of respiration and oxidative phosphorylation--carbonyl cyanide-3-chlorophenylhydrazone--in a medium without glucose was shown to drastically increase the interphase death rate of cells of both types, whereas this effect was not observed in a medium with glucose.
摘要
在用中国仓鼠和艾氏腹水瘤的辐照细胞进行的实验中，研究了能量供应对其间期死亡率的影响。结果表明，在不含葡萄糖的培养基中存在呼吸和氧化磷酸化解偶联剂——羰基氰化物-3-氯苯腙，会显著提高两种类型细胞的间期死亡率，而在含葡萄糖的培养基中未观察到这种效应。
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