Department of Infectious Diseases, Georgetown University Hospital, Washington, DC 20007, USA.
Infect Dis Clin North Am. 2013 Jun;27(2):285-304. doi: 10.1016/j.idc.2013.02.003. Epub 2013 Apr 3.
End-stage liver disease and hepatocellular carcinoma from chronic hepatitis C are the most common indications for orthotopic liver transplantation and the incidence of both are projected to increase over the next decade. Recurrent hepatitis C virus infection of the allograft is associated with an accelerated progression to cirrhosis, graft loss, and death. This article presents an overview of the natural history of hepatitis C virus recurrence in liver transplant recipients and guidance on optimal management strategies.
终末期肝病和肝细胞癌是慢性丙型肝炎最常见的肝移植适应证，预计在未来十年内这两种疾病的发病率都将增加。移植肝的丙型肝炎病毒再感染与肝硬化、移植物丢失和死亡的加速进展有关。本文介绍了肝移植受者丙型肝炎病毒复发的自然史概述，并就最佳管理策略提供了指导。
