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我们需要对所有小的浸润性乳腺癌和导管原位癌进行放射治疗吗?

Do we need to irradiate all small invasive breast cancers and DCIS?

作者信息

White Julia

机构信息

From the Department of Radiation Oncology, The James, Ohio State University Comprehensive Cancer Center.

出版信息

Am Soc Clin Oncol Educ Book. 2013:40-4. doi: 10.14694/EdBook_AM.2013.33.40.

DOI:10.14694/EdBook_AM.2013.33.40
PMID:23714451
Abstract

Breast radiotherapy after lumpectomy is considered standard for nearly all patients with invasive breast cancer and is recommended for many patients after lumpectomy for ductal carcinoma in situ (DCIS). However, there is recognition that lumpectomy alone can achieve optimal cancer control for some patients with invasive breast cancer and DCIS. Patients with breast cancers with lower risk of recurrence are less likely to derive benefit from breast radiotherapy. This review will focus on defining populations of patients with invasive breast cancer and DCIS with a low risk of recurrence post-lumpectomy and the evidence supporting omission of breast radiotherapy post-lumpectomy.

摘要

对于几乎所有浸润性乳腺癌患者,保乳术后进行乳房放疗被视为标准治疗方案,对于许多导管原位癌(DCIS)保乳术后的患者也推荐进行放疗。然而,人们认识到,对于一些浸润性乳腺癌和DCIS患者,单纯保乳手术即可实现最佳的癌症控制。复发风险较低的乳腺癌患者从乳房放疗中获益的可能性较小。本综述将重点关注确定保乳术后复发风险较低的浸润性乳腺癌和DCIS患者群体,以及支持保乳术后省略乳房放疗的证据。

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引用本文的文献

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Proportion and clinical outcomes of postoperative radiotherapy omission after breast-conserving surgery in women with breast cancer.保乳手术后乳腺癌女性术后放疗省略的比例和临床结局。
J Breast Cancer. 2015 Mar;18(1):50-6. doi: 10.4048/jbc.2015.18.1.50. Epub 2015 Mar 27.
2
The efficacy of molecular subtyping in predicting postoperative recurrence in breast-conserving therapy: a 15-study meta-analysis.分子亚型在预测保乳治疗术后复发中的疗效:一项纳入15项研究的荟萃分析。
World J Surg Oncol. 2014 Jul 15;12:212. doi: 10.1186/1477-7819-12-212.