Metzler Philipp, Zemann Wolfgang, Jacobsen Christine, Lübbers Heinz-Theo, Grätz Klaus Wilhelm, Obwegeser Joachim Anton
Department of Cranio-Maxillofacial and Oral Surgery, University of Zurich, Zurich, Switzerland.
J Craniofac Surg. 2013 May;24(3):753-7. doi: 10.1097/SCS.0b013e3182868b4f.
Long-term anthropometric follow-up of cranial vault growth may considerably add valuable information to current literature focusing on treatment strategies for premature multiple-suture craniosynostosis. The aim of this paper was to compare postoperative growth patterns of nonsyndromic and syndromic multiple-suture craniosynostotic children with sex-matched and age-matched children from the typically developing population. Forty-one multiple-suture craniosynostotic patients (19 nonsyndromic and 22 syndromic) were included in this 5-year follow-up. Anthropological data of sex-matched and age-matched normal Swiss children served as a control. A standardized time protocol for anthropometric skull measurements (head circumference and cephalic index) was used. Data were converted into Z-scores for standardized intercenter comparison. All patients showed a marked benefit in cranial vault shape after open skull remodeling. Significant differences in long-term cranial vault growth pattern could be seen between the nonsyndromic and the syndromic groups compared to the control group.
对颅穹窿生长进行长期人体测量随访，可为当前关注早发性多缝颅缝早闭治疗策略的文献提供大量有价值的信息。本文旨在比较非综合征性和综合征性多缝颅缝早闭儿童与性别和年龄匹配的正常发育儿童的术后生长模式。41例多缝颅缝早闭患者（19例非综合征性和22例综合征性）纳入了这项为期5年的随访研究。性别和年龄匹配的瑞士正常儿童的人类学数据作为对照。采用标准化的时间方案进行人体测量颅骨测量（头围和头指数）。数据转换为Z分数用于中心间标准化比较。所有患者在开放性颅骨重塑后颅穹窿形状均有明显改善。与对照组相比，非综合征性和综合征性组在颅穹窿长期生长模式上存在显著差异。
