Yang Yunqiang, Li Yang, Wu Yeke, Gu Yifei, Yin Heng, Long Hu, Shi Bing, Zheng Qian
Department of Stomatology, Tongji Hospital, Huazhong University of Science and Technology, Chengdu, China.
J Craniofac Surg. 2013 May;24(3):923-8. doi: 10.1097/SCS.0b013e3182587b34.
The aim of this study was to investigate the relevance of sex, age, and cleft type to velopharyngeal function after primary Sommerlad palatoplasty so as to improve velopharyngeal function after the procedure.
Records of 503 patients with nonsyndromic cleft palate after primary Sommerlad palatoplasty were included in the retrospective study. Relevance between their velopharyngeal function and sex, age, and cleft type was analyzed. Statistical analysis was performed using SPSS 13.0 (SPSS Inc., Chicago, IL).
There were no significant differences of velopharyngeal competence (VPC) rates between different sexes (P = 0.635). Specifically, VPC rates were significantly higher in younger-than-2-years groups than in older age groups (P < 0.05) and significantly lower in 6-years-or-older group (P < 0.05). No differences were found among 2- to 6-year-old groups (P > 0.05). The VPC rates were significantly lower in the bilateral complete cleft palate and the unilateral complete cleft palate than in the incomplete cleft palate before 2 years old (P < 0.05), whereas there were no significant differences totally (P = 0.875). Results showed that the disparity of the VPC rate among different cleft types would decrease with age. Moreover, results of multivariate logistic regression also indicated that operation age and cleft type are factors influencing velopharyngeal function.
Primary palatoplasty should be completed before 2 years old, and the postoperative velopharygeal function will greatly decreases after 6 years old. The influence of cleft type on velopharyngeal function is limited to young patients. For those who have missed the best surgical timing, appropriate delay of operation age is reasonable, especially for patients with complete cleft palate. For patients 4 to 6 years old, the first choice is still simple palatoplasty no matter which cleft type they are classified into.
本研究旨在探讨初次Sommerlad腭成形术后性别、年龄和腭裂类型与腭咽功能的相关性,以改善术后腭咽功能。
本回顾性研究纳入了503例初次Sommerlad腭成形术后的非综合征性腭裂患者。分析了他们的腭咽功能与性别、年龄和腭裂类型之间的相关性。使用SPSS 13.0(SPSS公司,伊利诺伊州芝加哥)进行统计分析。
不同性别之间的腭咽闭合能力(VPC)率无显著差异(P = 0.635)。具体而言,2岁以下组的VPC率显著高于年龄较大组(P < 0.05),6岁及以上组的VPC率显著较低(P < 0.05)。2至6岁组之间未发现差异(P > 0.05)。双侧完全性腭裂和单侧完全性腭裂的VPC率在2岁之前显著低于不完全性腭裂(P < 0.05),而总体上无显著差异(P = 0.875)。结果表明,不同腭裂类型之间的VPC率差异会随着年龄增长而减小。此外,多因素逻辑回归结果还表明,手术年龄和腭裂类型是影响腭咽功能的因素。
初次腭成形术应在2岁之前完成,6岁之后术后腭咽功能将大幅下降。腭裂类型对腭咽功能的影响仅限于年轻患者。对于错过最佳手术时机的患者,适当推迟手术年龄是合理的,尤其是对于完全性腭裂患者。对于4至6岁的患者,无论其属于哪种腭裂类型,首选仍然是简单腭成形术。