Sözen Esra, Tansuker Deniz, Yldrm Ömürsen, Uçal Yusuf Orhan, Coşkun Berna Uslu
Department of Otolaryngology-Head and Neck Surgery, Şişli Etfal Training and Research Hospital, İstanbul, Türkiye.
J Craniofac Surg. 2013 May;24(3):e314-8. doi: 10.1097/SCS.0b013e31828f2e56.
This study aimed to compare the effectiveness of radiofrequency ablation (RFA) and intranasal steroid (INS) treatments on respiratory and olfactory functions in patients with inferior concha hypertrophy and chronic nasal obstruction.
This was a prospective clinical trial performed at a tertiary referral center.
We assessed patients with nasal obstruction between July 2011 and February 2012. The severity of the nasal obstruction in both groups was determined before treatment and 3 months after using a visual analog scale. For the purpose of an objective test, assessment was performed by the acoustic rhinometry. Using Sniffin' Sticks for test odor identification, the discrimination and thresholds were assessed in both groups.
The visual analog scale score after treatment was significantly lower in each group. Radiofrequency ablation treatment significantly improved the right minimal cross-sectional area 1 (MCA1), mean MCA1, and volume 1, as well as the right MCA2, mean MCA2, volume 2, and total volume. In the INS group, improvement was detected for the left MCA1, mean MCA1, and volume 1. Minimal cross-sectional area 2, volume 2, and total volume improved significantly after RFA treatment, but not after INS treatment.
Although RFA may be more effective in the posterior region of the nasal cavity, INS and RFA used in the treatment of inferior concha hypertrophy both had favorable effects on respiratory function. Intranasal steroid treatment provided improved discrimination and total score values, whereas RFA treatment improved only odor identification.
本研究旨在比较射频消融(RFA)和鼻内类固醇(INS)治疗对下鼻甲肥大和慢性鼻塞患者呼吸及嗅觉功能的有效性。
这是一项在三级转诊中心进行的前瞻性临床试验。
我们评估了2011年7月至2012年2月期间的鼻塞患者。两组患者在治疗前及治疗3个月后,使用视觉模拟量表确定鼻塞的严重程度。为进行客观测试,采用鼻声反射仪进行评估。使用Sniffin' Sticks测试气味识别能力,对两组患者的辨别能力和阈值进行评估。
每组治疗后的视觉模拟量表评分均显著降低。射频消融治疗显著改善了右侧最小横截面积1(MCA1)、平均MCA1和容积1,以及右侧MCA2、平均MCA2、容积2和总体积。在INS组中,左侧MCA1、平均MCA1和容积1有所改善。RFA治疗后,最小横截面积2、容积2和总体积显著改善,但INS治疗后未改善。
虽然RFA在鼻腔后部区域可能更有效,但INS和RFA用于治疗下鼻甲肥大对呼吸功能均有良好效果。鼻内类固醇治疗可提高辨别能力和总分值,而RFA治疗仅改善气味识别能力。