Schneider Maria Victoria
The Genome Analysis Centre, Norwich Research Park, Norwich, UK.
Methods Mol Biol. 2013;1021:1-11. doi: 10.1007/978-1-62703-450-0_1.
Here we provide a broad overview of the definition of the term "systems biology" as well as pinpoint specific events in biological research and beyond that are consistently cited to have contributed and led to the current science of in silico systems biology. Since there have been many reviews and historical accounts describing the term, it would be impossible to include all single references. However, we do attempt to provide a consensus vision of how the field has evolved and consequently the terminology that followed it. We also highlight the development and general acceptance, and use, of standards for model representations as being crucial to the continued success of the in silico systems biology field.
在此，我们对“系统生物学”这一术语的定义进行广泛概述，并指出生物学研究及其他领域中一些特定事件，人们一直认为这些事件为当前的计算机模拟系统生物学科学做出了贡献并引领了其发展。由于已有许多综述和历史记载描述了该术语，所以不可能涵盖所有单一参考文献。然而，我们确实试图就该领域的发展历程以及随之而来的术语提供一个共识性的观点。我们还强调模型表示标准的发展、普遍接受和应用对于计算机模拟系统生物学领域持续取得成功至关重要。
