Chugh Shikha, Sarkar Rashmi, Garg Vijay K, Singh Avninder, Keisham Chitralekha
Department of Dermatology, Maulana Azad Medical College and Associated Lok Nayak Hospital, New Delhi, India.
Indian J Dermatol. 2013 Mar;58(2):142-4. doi: 10.4103/0019-5154.108057.
Cyclooxygenase-2 (COX-2) inhibitors are rapidly becoming the first choice nonsteroidal anti-inflammatory drugs (NSAIDs) for various rheumatological and other painful conditions. However, they might not be as safe or free of side effects as they are considered to be. These COX-2inhibitors may cause a variety of dermatological and systemic side effects of which we should be aware to avoid their indiscriminate use. We hereby report a case of multifocal fixed drug eruption (FDE) with celecoxib which has not yet been reported in Indian settings.
环氧化酶-2（COX-2）抑制剂正迅速成为治疗各种风湿性疾病和其他疼痛性疾病的首选非甾体抗炎药（NSAIDs）。然而，它们可能并不像人们认为的那样安全或无副作用。这些COX-2抑制剂可能会引起各种皮肤和全身性副作用，我们应该对此有所了解，以避免滥用。我们在此报告一例使用塞来昔布后出现多灶性固定性药疹（FDE）的病例，这种情况在印度尚未见报道。
