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[因畸形导致梗阻性尿路病的儿童肾移植结果]

[Results of renal transplantation in children with obstructive uropathy due to malformations].

作者信息

Squifflet J P, Caramuta U, Gianello P, Wese F, Opsomer R J, Alexandre G P

机构信息

Service de transplantation rénale et pancréatique, Université catholique de Louvain.

出版信息

Acta Urol Belg. 1990;58(1):63-71.

PMID:2371939
Abstract

180 renal transplants have been performed at our center in children less than 15 years old. Even if the distribution is equivalent (50/50%) between kidneys from living and cadaver donors, graft actuarial survival rate is 20% better at 5 years in the first group. 42 grafts have been implanted for end-stage renal failure due to chronic pyelonephritis (CNP). Among them, 17 were due to obstructive L.U.T. uropathies (posterior urethral valves): even if the results are identical in that subgroup compared to CPN group, there is an increased morbidity risk as 2 ureterovesical stenosis and 1 secondary vesico-ureteral reflux were observed (3/17 versus 4/163 in the remnant population).

摘要

我们中心已为15岁以下儿童进行了180例肾移植手术。即使活体供肾和尸体供肾的分配比例相同(各占50%),第一组的移植肾实际存活率在5年时仍比第二组高20%。42例移植肾因慢性肾盂肾炎(CNP)导致终末期肾衰竭而植入。其中,17例是由于下尿路梗阻性尿路病(后尿道瓣膜):即使该亚组与慢性肾盂肾炎组的结果相同,但发病率风险有所增加,因为观察到2例输尿管膀胱狭窄和1例继发性膀胱输尿管反流(17例中有3例,其余人群中163例中有4例)。

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