Kobatake Yui, Miyabayashi Takayoshi, Yada Naoko, Kachi Shingo, Ohta George, Sakai Hiroki, Maeda Sadatoshi, Kamishina Hiroaki
Ozawa Animal Hospital, 4 Ujiniban, Uji, Kyoto 611-0021, Japan.
J Vet Med Sci. 2013 Oct;75(10):1379-81. doi: 10.1292/jvms.12-0550. Epub 2013 May 28.
A 12-week-old female Wire-haired miniature dachshund presented with non-progressive ataxia and hypermetria. Due to the animal's clinical history and symptoms, cerebellar malformations were suspected. Computed tomography (CT) and magnetic resonance imaging (MRI) detected bilateral ventriculomegaly, dorsal displacement of the cerebellar tentorium, a defect in the cerebellar tentorium and a large fluid-filled cystic structure that occupied the regions where the cerebellar vermis and occipital lobes are normally located. The abovementioned cystic structure and the defect in the cerebellar tentorium were comparable to those seen in humans with Dandy-Walker syndrome. However, the presence of the cystic structure in the occipital lobe region was unique to the present case. During necropsy, the MRI findings were confirmed, but the etiology of the condition was not determined.
一只12周龄的雌性刚毛迷你腊肠犬出现非进行性共济失调和辨距不良。根据该动物的临床病史和症状,怀疑存在小脑畸形。计算机断层扫描(CT)和磁共振成像(MRI)检测到双侧脑室扩大、小脑幕背侧移位、小脑幕缺损以及一个大的充满液体的囊性结构,该结构占据了小脑蚓部和枕叶正常所在的区域。上述囊性结构和小脑幕缺损与患有丹迪-沃克综合征的人类所见相似。然而,枕叶区域存在囊性结构是本病例所特有的。尸检时,MRI检查结果得到证实,但该病症的病因尚未确定。