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用于固定因福尼尔坏疽导致的泌尿生殖组织缺损中自体皮片移植的2-辛基氰基丙烯酸酯胶水:一项初步试验

2-octyl-cyanoacrylate glue for fixation of STSG in genitourinary tissue defects due to Fournier gangrene: a preliminary trial.

作者信息

Sivrioğlu Nazan, Irkören Saime, Ceylan Ender, Sonel Ali Murat, Copçu Eray

机构信息

Department of Plastic Surgery, Adnan Menderes University Faculty of Medicine, Aydın, Turkey.

出版信息

Ulus Travma Acil Cerrahi Derg. 2013 May;19(3):215-8. doi: 10.5505/tjtes.2013.92256.

Abstract

BACKGROUND

In these reported cases, we observed the outcomes of skin take and wound healing using 2-octyl-cyanoacrylate glue, which was used as tissue glue in the reconstruction of complex genital skin loss due to fournier gangrene.

METHODS

Fifteen patients with Fournier's gangrene were treated in this study. After initial surgical debridement, all defects were repaired using STSG. In this method a thin layer of 2-octyl-cyanoacrylate was dripped on the recipient site immediately before graft application. All wounds were followed up postoperatively and observed for evidence of graft take, seroma or hematoma formation, drainage, and infection. Patient and physician satisfaction were also determined.

RESULTS

Grafts were completely accepted in all fifteen patients. None of the patients had wound infection, seroma, hematoma, or other complications.

CONCLUSION

Use of 2-octyl-cyanoacrylate glue (Glueseal) for STSG fixation in complex genital skin defects after Fournier gangrene may be an acceptable alternative to conventional surgical closure with a good cosmetic outcome. Further studies are needed to confirm our initial success with this approach.

摘要

背景

在这些报告的病例中,我们观察了使用2-辛基氰基丙烯酸酯胶水进行植皮和伤口愈合的结果,该胶水在因福尼尔坏疽导致的复杂生殖器皮肤缺损重建中用作组织胶水。

方法

本研究治疗了15例福尼尔坏疽患者。在初始手术清创后,所有缺损均采用自体皮片移植修复。在这种方法中,在移植皮片应用前立即在受区滴上一层薄薄的2-辛基氰基丙烯酸酯。所有伤口术后均进行随访,观察植皮成活、血清肿或血肿形成、引流及感染情况。还确定了患者和医生的满意度。

结果

所有15例患者的移植皮片均完全成活。所有患者均未发生伤口感染、血清肿、血肿或其他并发症。

结论

在福尼尔坏疽后复杂生殖器皮肤缺损中使用2-辛基氰基丙烯酸酯胶水(Glueseal)进行自体皮片移植固定可能是传统手术缝合的一种可接受的替代方法,具有良好的美容效果。需要进一步研究来证实我们采用这种方法的初步成功。

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