Egerod Israelsen Mads, Gluud Lise Lotte, Bendtsen Flemming, Møller Søren, Krag Aleksander Ahm
Medicinsk Afdeling F, Gentofte Hospital, Denmark.
Ugeskr Laeger. 2013 May 27;175(22):1562-6.
Cirrhosis, ascites and renal impairment are associated with high morbidity and mortality. The hepatorenal syndrome (HRS) is a type of renal failure that affects patients with cirrhosis and ascites. This paper provides an update on evidence-based interventions in HRS. A number of factors can precipitate HRS. The monitoring, prevention, early detection, and correct treatment of these are essential. Terlipressin combined with albumin is the first-line treatment of type 1 HRS. In type 2 HRS with refractory ascites, liver transplantation and TIPS should be considered.
肝硬化、腹水和肾功能损害与高发病率和死亡率相关。肝肾综合征(HRS)是一种影响肝硬化和腹水患者的肾衰竭类型。本文提供了关于肝肾综合征循证干预措施的最新信息。多种因素可促使肝肾综合征发生。对这些因素进行监测、预防、早期检测及正确治疗至关重要。特利加压素联合白蛋白是1型肝肾综合征的一线治疗方法。对于伴有顽固性腹水的2型肝肾综合征,应考虑肝移植和经颈静脉肝内门体分流术(TIPS)。