Kadlub Natacha, Kreindel Tamara, Belle Mbou Valère, Coudert Amélie, Ansari Edward, Descroix Vianney, Ruhin-Poncet Blandine, Coulomb L'hermine Aurore, Berdal Ariane, Vazquez Marie-Paule, Ducou Lepointe Hubert, Picard Arnaud
APHP, Hôpital Necker Enfant Malades (Head of the Department: Vazquez), Service de chirurgie maxillo-faciale, Paris F75015, France; Université Paris 5, UFR médecine Paris Descartes, Paris F75006, France; Centre de références des malformations de la face et de la cavité buccale (Head of the Department: Vazquez), France; Laboratoire de Physiopathologie orale et Moléculaire (Head of the Department: Berdal), INSERM, UMRS 872, Equipe 5, Centre de recherche des Cordeliers, Paris 75006, France.
APHP, Hôpital Armand Trousseau (Head of the Department: Ducou Lepointe), Service d'Imagerie Médicale, Paris F75012, France; Université Pierre et Marie Curie 6, UFR médecine Pierre et Marie Curie, Paris F75005, France.
J Craniomaxillofac Surg. 2014 Mar;42(2):125-31. doi: 10.1016/j.jcms.2013.03.007. Epub 2013 May 27.
Characteristics and epidemiology of jaw tumours have been described mostly in adults. Compared with their adult counterparts, childhood jaw tumours show considerable differences. The aim of this study was to describe the different jaw tumours in children, define diagnostic tools to determine their specificity and describe optimal treatment.
All children patients with jaw lesions, excluding cysts, apical granuloma and osteitis were included in our study between 1999 and 2009. The medical records were analyzed for clinical, radiological, and pathological findings, treatments and recurrences.
Mean patient age was 10.9 years old, ranging from 2 months to 18 years old. Of the 63 lesions, 18 were odontogenic and 45 non-odontogenic lesions. 6% of all cases were malignant tumours; the mean age of presentation was 7.25 years old, [ranging from 0.2 to 18 years old]. Approximately 80% of the tumours developed after 6 years of age. Odontogenic tumours occurred more often after the age of 6.
Compared with their adult counterpart, childhood jaw tumours show considerable differences in their clinical behaviour and radiological and pathological characteristics. Clinical features of some tumours can be specific to children. Tumourigenesis is related to dental development and facial growth. Conservative treatment should be considered.
颌骨肿瘤的特征和流行病学大多是在成人中描述的。与成人颌骨肿瘤相比，儿童颌骨肿瘤存在显著差异。本研究的目的是描述儿童颌骨的不同肿瘤，确定诊断工具以明确其特异性，并描述最佳治疗方法。
1999年至2009年间，我们纳入了所有患有颌骨病变的儿童患者，但不包括囊肿、根尖肉芽肿和骨炎。对病历进行了临床、放射学和病理学检查结果、治疗方法及复发情况的分析。
患者平均年龄为10.9岁，年龄范围从2个月至18岁。在63例病变中，18例为牙源性病变，45例为非牙源性病变。所有病例中6%为恶性肿瘤；出现症状的平均年龄为7.25岁，[年龄范围从0.2岁至18岁]。约80%的肿瘤在6岁以后发生。牙源性肿瘤在6岁以后更常出现。
与成人颌骨肿瘤相比，儿童颌骨肿瘤在临床行为、放射学和病理学特征方面存在显著差异。一些肿瘤的临床特征在儿童中具有特异性。肿瘤发生与牙齿发育和面部生长有关。应考虑保守治疗。
