MOE Key Laboratory of Bioinformatics; School of Life Sciences; Tsinghua University; Beijing, China.
Autophagy. 2013 Aug;9(8):1247-8. doi: 10.4161/auto.25176. Epub 2013 May 29.
Autophagy is an evolutionarily conserved process in eukaryotic cells that functions to degrade cytoplasmic components in the vacuole or lysosome. Previous research indicates that the core molecular machinery of autophagosome formation works well in plants, and plant autophagy plays roles in diverse biological processes such as nutrient recycling, development, immunity and responses to a variety of abiotic stresses. Recently, we reported that autophagy contributed to leaf starch degradation, which had been thought to be a process confined to chloroplasts. This finding demonstrated a previously unidentified pathway of leaf starch depletion and a new role of basal autophagy in plants.
自噬是真核细胞中一种进化上保守的过程,其功能是在液泡或溶酶体中降解细胞质成分。以前的研究表明,自噬体形成的核心分子机制在植物中运作良好,植物自噬在多种生物过程中发挥作用,如营养物质回收、发育、免疫和对各种非生物胁迫的反应。最近,我们报道了自噬有助于叶片淀粉的降解,而这一过程曾被认为仅限于叶绿体。这一发现证明了叶片淀粉耗竭的一条以前未被识别的途径,以及基础自噬在植物中的一个新作用。