Watson W J, Cefalo R C
Department of Obstetrics and Gynecology, University of North Carolina, Chapel Hill 27514.
Am J Perinatol. 1990 Jul;7(3):251-3. doi: 10.1055/s-2007-999493.
Tocolysis can be used to arrest contractions in selected patients with placenta previa if the maternal condition is stable. Over a 5-year period, 41 patients with symptomatic placenta previa were treated, of whom 18 were given magnesium sulfate therapy for tocolysis. The mean prolongation of gestation was 18.5 days, and tocolysis was successful in 17 of 18 cases. Since betamimetic drugs used for tocolysis may mask or blunt maternal cardiovascular responses to volume depletion, magnesium sulfate is a better choice to inhibit contractions in patients with symptomatic placenta previa whose bleeding is mild or moderate.
如果母体状况稳定，在部分前置胎盘患者中可使用宫缩抑制剂来抑制宫缩。在5年期间，对41例有症状的前置胎盘患者进行了治疗，其中18例给予硫酸镁进行宫缩抑制治疗。妊娠平均延长18.5天，18例中有17例宫缩抑制成功。由于用于宫缩抑制的β-拟交感神经药物可能掩盖或减弱母体对容量减少的心血管反应，对于出血为轻度或中度的有症状前置胎盘患者，硫酸镁是抑制宫缩的更好选择。
