Combs C A, Walker C, Matlock B A, Crombleholme W
Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California, San Francisco.
Am J Perinatol. 1990 Jul;7(3):287-9. doi: 10.1055/s-2007-999504.
A case is presented of a primigravida with transient diabetes insipidus, gestational hypertension, and multiple seizures resistant to magnesium sulfate and diazepam. After addition of phenytoin, no further seizures occurred. Transient diabetes insipidus in pregnancy has been previously associated with hypertension, liver dysfunction, and fetal distress. Considered with previous cases, it is suggested that seizures may frequently be part of this syndrome.
本文报告一例初产妇,患有暂时性尿崩症、妊娠高血压,且多次癫痫发作,硫酸镁和地西泮治疗无效。加用苯妥英钠后,未再发生癫痫发作。妊娠期间的暂时性尿崩症既往与高血压、肝功能障碍及胎儿窘迫有关。结合既往病例来看,提示癫痫发作可能常为此综合征的一部分。