Centre Henri Becquerel.
Blood. 2013 May 30;121(22):4433-4. doi: 10.1182/blood-2013-04-493486.
In this issue of Blood, Li et al report mutations in the 3′ untranslated region (3′UTR) of TP53 that modify the expression of p53 and thus its effect on response to therapy in diffuse large B-cell lymphoma (DLBCL) patients.
在本期《Blood》中,Li 等人报告了 TP53 的 3′非翻译区(3′UTR)突变,这些突变改变了 p53 的表达,从而影响了弥漫性大 B 细胞淋巴瘤(DLBCL)患者对治疗的反应。