Bandyopadhyay Anis, Das Mou, Jana Sukumar, Das Anuradha
Department of Radiotherapy, Calcutta National Medical College and Hospital, Kolkata, India.
Indian J Dermatol. 2013 May;58(3):241. doi: 10.4103/0019-5154.110849.
Acrospiroma denotes a group of benign ductal tumours of the eccrine sweat glands that may or may not be connected to the skin. Although various eccrine sweat gland tumours including benign acrospiroma are widely reviewed, malignant acrospiroma is rarely reported. Malignant acrospiroma have the propensity to recur locally and metastasizes to regional lymph nodes. The primary treatment is wide local excision with or without lymph node dissection. Local radiation is added in the presence of high risk features to reduce the risk of recurrence. We describe a case of a malignant acrospiroma involving wide areas of chest and abdominal wall with metastases to bilateral axillary lymph nodes in a 47 year old man showing minimal clinical response to combination chemotherapy and paclitaxel.
顶泌汗腺腺瘤是指一组发生于小汗腺的良性导管肿瘤，可与皮肤相连，也可不相连。尽管包括良性顶泌汗腺腺瘤在内的各种小汗腺肿瘤已得到广泛综述，但恶性顶泌汗腺腺瘤的报道却很少。恶性顶泌汗腺腺瘤有局部复发并转移至区域淋巴结的倾向。主要治疗方法是广泛局部切除，可联合或不联合淋巴结清扫。存在高危特征时加用局部放疗以降低复发风险。我们报告一例47岁男性，患有累及胸壁和腹壁广泛区域并伴有双侧腋窝淋巴结转移的恶性顶泌汗腺腺瘤，该患者对联合化疗和紫杉醇治疗的临床反应甚微。
