Department of Environmental Health Sciences, IRCCS-Istituto di Ricerche Farmacologiche "Mario Negri", Via Giuseppe La Masa 19, 20156 Milan, Italy.
Chemosphere. 2013 Sep;93(2):338-43. doi: 10.1016/j.chemosphere.2013.04.086. Epub 2013 May 29.
We analyzed polychlorobiphenyls (PCBs), perfluorooctanesulfonate (PFOS) and perfluorooctanoate (PFOA) in the edible part of farmed sea bass reared in two fish farms in Liguria (Northern Italy). The aim was to determine the contamination levels and human exposure to these chemicals through fish consumption. Concentrations of "dioxin-like" PCBs (DL-PCBs) ranged from 0.033 to 0.759pg ΣTEQ-PCBg(-1) whole weight (w.w.) in fish farm 1 and from 0.032 to 1.60pg ΣTEQ-PCBg(-1) w.w. in fish farm 2, and the six indicators of "non-dioxin-like" (NDL-PCBs) from 0.538 to 9.33ng Σ6PCBg(-1) w.w. and from 1.62 to 27.6ng Σ6PCBg(-1) w.w. Concentrations were generally lower in farm 1 than in farm 2. One reason for this difference might be the proximity of farm 2 to the seaport of La Spezia, which could be a punctual source of pollutants influencing the contamination of the water in the farm. Principal component analysis (PCA) showed differences also in the congeners profiles for the two sites, with higher-chlorinated PCBs more abundant in farm 1, and lower-chlorinated PCBs were more abundant in farm 2. Most of the concentrations of PFOS and PFOA were below the limit of detection (LOD 0.05ngg(-1) w.w.). Only about 10% of the samples analyzed had levels slightly higher than the LOD. Assessments of exposure using these data showed that consumption of farmed fish may contribute significantly to PCBs through the diet, whereas the contribution of PFOS and PFOA seems to be low.
我们分析了在意大利北部利古里亚的两个养殖场养殖的鲈鱼可食用部分中的多氯联苯 (PCBs)、全氟辛烷磺酸 (PFOS) 和全氟辛酸 (PFOA)。目的是确定通过鱼类消费这些化学品的污染水平和人体暴露情况。鱼场 1 中“类二恶英”多氯联苯 (DL-PCBs) 的浓度范围为 0.033 至 0.759pg ΣTEQ-PCBg(-1) 全重 (w.w.)，鱼场 2 中的浓度范围为 0.032 至 1.60pg ΣTEQ-PCBg(-1) w.w.，“非类二恶英”(NDL-PCBs) 的 6 种指标浓度范围为 0.538 至 9.33ng Σ6PCBg(-1) w.w.和 1.62 至 27.6ng Σ6PCBg(-1) w.w.。鱼场 1 的浓度通常低于鱼场 2。造成这种差异的一个原因可能是鱼场 2 靠近拉斯佩齐亚海港，这可能是一个影响养殖场水污染物的临时污染源。主成分分析 (PCA) 还显示了两个地点的同系物分布存在差异，高氯代 PCBs 在鱼场 1 中更为丰富，而低氯代 PCBs 在鱼场 2 中更为丰富。大多数 PFOS 和 PFOA 的浓度低于检测限 (LOD 0.05ngg(-1) w.w.)。只有约 10%的分析样本的水平略高于 LOD。使用这些数据进行的暴露评估表明，通过饮食，养殖鱼类的消费可能会显著增加对 PCBs 的摄入量，而 PFOS 和 PFOA 的摄入量似乎较低。
