Gozdowska J, Jankowski K, Bieniasz M, Wszoła M, Domagała P, Kieszek R, Lewandowska D, Urbanowicz A, Szmidt J, Grenda R, Kwiatkowski A, Chmura A, Durlik M
Department of Transplantation Medicine and Nephrology, Medical University of Warsaw, Warsaw, Poland.
Transplant Proc. 2013 May;45(4):1347-50. doi: 10.1016/j.transproceed.2013.01.030.
Kidney transplantation is efficacious as a renal replacement, particularly pre-emptive living donation. In Poland, the rate of transplantation of living donor kidneys is only 3%. The aim of the study was to identify the most common reasons to disqualify a potential living kidney donor.
We evaluated 124 kidney donor candidates for 111 potential recipients at 1 medical center for genders and ages of donor and recipient; thus relation, donor disqualification reasons, number of potential donors for a particular recipient, prior transplantations, and kidney vasculature.
The 111 recipients of ages 2-62 years had, 1, 2, or 3 potential donors were tested in 101, 1, and 7, cases respectively. We had 18.9% recipients referred for pre-emptive transplantation; 59.5% were on haemodialysis and 21.6% on peritoneal dialysis. In all, 89% recipients sought first kidney transplantations. Kidneys were procured from 49/124 (39.5%) of the initially evaluated donors. The full examination was completed by 92 potential donors with 68/124 donors disqualified early. Single and multiple renal arteries were detected in 56 and 36 potential donors, respectively. Donor disqualification was due to medical contraindications (39.7%), earlier transplantation from a deceased donor (25%), immunologic constraints (23.5%), donor consent withdrawn (6%) or psychological and social reasons (4.4%).
A considerable number of donor candidates are disqualified for medical reasons.
肾移植作为一种肾脏替代疗法是有效的，尤其是预先进行的活体肾捐赠。在波兰，活体供肾的移植率仅为3%。本研究的目的是确定潜在活体肾捐赠者被取消资格的最常见原因。
我们在1个医疗中心评估了124名肾捐赠候选者，以确定111名潜在受者的供者和受者的性别与年龄、亲属关系、供者被取消资格的原因、特定受者的潜在供者数量、既往移植情况以及肾脏血管系统。
111名年龄在2至62岁的受者中，分别有101例、1例和7例接受了1名、2名或3名潜在供者的检测。18.9%的受者被转诊进行预先移植；59.5%的受者接受血液透析，21.6%的受者接受腹膜透析。总体而言，89%的受者首次寻求肾移植。从最初评估的124名供者中的49名（39.5%）获取了肾脏。92名潜在供者完成了全面检查，124名供者中有68名提前被取消资格。分别在56名和36名潜在供者中检测到单支和多支肾动脉。供者被取消资格的原因包括医学禁忌（39.7%）、既往接受已故供者的移植（25%）、免疫限制（23.5%）、供者撤回同意（6%）或心理和社会原因（4.4%）。
相当数量的供者候选者因医学原因被取消资格。
