Department of Physical Medicine & Rehabilitation, Chonbuk National University Medical School, Jeonju, Jeonbuk, Republic of Korea.
Neurosci Lett. 2013 Aug 26;548:181-4. doi: 10.1016/j.neulet.2013.05.037. Epub 2013 May 28.
Previous studies have established that transcranial direct current stimulation (tDCS) is a powerful technique for the deliberate manipulation of the activity of human cerebral cortex. Moreover, it has also been shown that the non-exhausted voluntary motor exercise increases the excitability of corticospinal tract. We conducted this study to define the facilitation effect following anodal tDCS combined with the voluntary grip exercise as compared with single use of tDCS or voluntary grip exercise. Our result showed that the combination of anodal tDCS with voluntary grip exercise produced a 2-fold increase in the amplitude of MEP as compared with single use of anodal tDCS or voluntary grip exercise. In conclusion, our result could indicate that the treatment outcomes of brain and neurorehabilitation using tDCS would be better when tDCS is combined with the appropriate method of voluntary exercise as compared with single use of tDCS.
先前的研究已经证实，经颅直流电刺激（tDCS）是一种强大的技术，可以有意地操纵人类大脑皮层的活动。此外，也已经表明，非耗竭性的自愿运动锻炼会增加皮质脊髓束的兴奋性。我们进行这项研究的目的是确定与单独使用 tDCS 或自愿握力运动相比，阳极 tDCS 联合自愿握力运动后的促进作用。我们的结果表明，与单独使用阳极 tDCS 或自愿握力运动相比，阳极 tDCS 联合自愿握力运动可使 MEP 的振幅增加 2 倍。总之，我们的结果可能表明，与单独使用 tDCS 相比，当 tDCS 与适当的自愿运动方法相结合时，使用 tDCS 进行大脑和神经康复的治疗效果会更好。
