Department of Cosmeceutics, China Medical University, No. 91, Hsueh-Shih Rd., Taichung 40402, Taiwan.
Phys Chem Chem Phys. 2013 Jul 21;15(27):11275-86. doi: 10.1039/c3cp50956g. Epub 2013 Jun 3.
This study deals with the preparation of multi-shaped nanoscale gold crystals under synthetically simple, green, and efficient conditions using a seed-mediated growth approach in the presence of hyaluronic acid (HA). These highly biocompatible multi-shaped gold nanocrystals were examined to evaluate their catalytic and surface enhanced Raman scattering (SERS) properties. The results show that the size and shape of the nanocrystals are mainly correlated to the amount of seed, seed size, HA concentration, and reaction temperature. Gold seeds accelerate the reduction of the gold precursor to form gold nanocrystals using HA. The HA serves as a reducing agent and a growth template for the reduction of Au(III) and nanocrystal stabilization. The multi-shaped gold nanocrystals showed superior catalytic properties and higher SERS performance. The simple, green approach efficiently controls the nanocrystals and creates many opportunities for future applications.
本研究采用种子介导生长法，在透明质酸（HA）存在的条件下，在合成简单、绿色、高效的条件下制备多形状纳米金晶体。这些高生物相容性的多形状金纳米晶体被用于评估它们的催化和表面增强拉曼散射（SERS）性质。结果表明，纳米晶体的尺寸和形状主要与种子量、种子尺寸、HA 浓度和反应温度有关。金种子加速了使用 HA 还原金前驱体形成金纳米晶体的过程。HA 既作为 Au(III) 还原的还原剂，又作为纳米晶稳定的生长模板。多形状金纳米晶体表现出优异的催化性能和更高的 SERS 性能。这种简单、绿色的方法能够有效地控制纳米晶体，并为未来的应用创造了许多机会。
