基于荧光共振能量转移（FRET）的比率型荧光探针用于选择性 Fe3+ 传感及其在线粒体中的应用。
FRET-based ratiometric fluorescent probes for selective Fe3+ sensing and their applications in mitochondria.
机构信息
State Key Laboratory of Fine Chemicals, School of Chemical Engineering, Dalian University of Technology, Dalian, 116024, China.
出版信息
Dalton Trans. 2013 Jul 28;42(28):10093-6. doi: 10.1039/c3dt50832c.
PMID:23728488
Abstract
Efficient ratiometric fluorescent Fe(3+) probes were designed and synthesized by linking a conjugated naphthalene chromophore to a rhodamine platform and a lipophilic triphenylphosphonium (TPP) cation. The probes could sensitively and selectively detect mitochondrial Fe(3+) in living cells.
摘要
设计并合成了高效比率型荧光 Fe(3+)探针，通过将共轭萘基发色团与罗丹明平台和疏水性三苯基膦（TPP）阳离子连接。该探针能够在活细胞中灵敏且选择性地检测线粒体 Fe(3+)。
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