Mackelprang Romel D, Bosire Rose, Guthrie Brandon L, Choi Robert Y, Liu Amy, Gatuguta Anne, Rositch Anne F, Kiarie James N, Farquhar Carey
Department of Epidemiology, University of Washington, 325 Ninth Avenue, Seattle, WA, 98104, USA,
AIDS Behav. 2014 Jan;18(1):189-93. doi: 10.1007/s10461-013-0529-6.
HIV-1 serodiscordant couples may experience increased risks of relationship dissolution; however, longitudinal stability of these relationships is poorly understood. We determined rates and correlates of separation among 469 serodiscordant couples in Nairobi and found that 113 (24 %) separated during 2 years of follow-up. Couples with a female HIV-1 infected partner (F+M-) and no income were more likely to separate than M+F- couples without income (HR = 5.0; 95 % CI 1.1-25.0), and F+M- and M+F- couples with income (HR = 2.4; 95 % CI 1.3-4.5 and HR = 2.3; 95 % CI 1.2-4.8, respectively). High separation rates may be important for couple support services and for conducting discordant couple studies.
一方感染HIV-1的伴侣关系解体风险可能会增加;然而,这类伴侣关系的长期稳定性却鲜为人知。我们确定了内罗毕469对一方感染HIV-1的伴侣的分居率及其相关因素,发现在2年的随访期内有113对(24%)分居。女性感染HIV-1的伴侣(F+M-)且没有收入的伴侣比没有收入的男性感染HIV-1的伴侣(M+F-)更有可能分居(风险比=5.0;95%置信区间1.1-25.0),以及有收入的F+M-和M+F-伴侣(风险比分别为2.4;95%置信区间1.3-4.5和2.3;95%置信区间1.2-4.8)。高分居率对于伴侣支持服务以及开展一方感染的伴侣研究可能具有重要意义。