Bütow K W
Department of Maxillo-Facial and Oral Surgery, University of Pretoria, South Africa.
Cleft Palate J. 1990 Jul;27(3):241-51; discussion 251-2. doi: 10.1597/1545-1569(1990)027<0241:cgdasb>2.3.co;2.
The purpose of this study was to create craniofacial growth disturbances via synostoses of sutures of the cranial base, as well as of other various selected sutures of the anterior cranial and posterior facial structures. Twelve sutures, single or in combination, were obliterated by means of autogenous bone transplantation in twenty-five baby baboons (Papio ursinus). The data obtained from the sacrificed animals were qualitatively analyzed. The results indicated that synostosis of any of the selected sutures does lead to craniofacial growth disturbances. Furthermore, no specific synostosed suture could be identified that might cause a specific type of craniofacial dysostosis, although unilateral facial deformities always occurred after unilateral suture synostosis.
本研究的目的是通过颅底缝线以及前颅和后面部结构的其他各种选定缝线的骨性融合来造成颅面生长紊乱。在25只幼年狒狒（山魈）中，通过自体骨移植使12条缝线单独或联合闭塞。对处死动物所获得的数据进行了定性分析。结果表明，任何选定缝线的骨性融合确实会导致颅面生长紊乱。此外，虽然单侧缝线骨性融合后总是出现单侧面部畸形，但未发现可能导致特定类型颅面骨发育不全的特定骨性融合缝线。
