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本文引用的文献

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[Alendronate treatment of osteoporosis secondary to Duchenne muscular dystrophy].[阿仑膦酸钠治疗杜氏肌营养不良继发的骨质疏松症]
An Pediatr (Barc). 2011 Feb;74(2):122-5. doi: 10.1016/j.anpedi.2010.10.002. Epub 2010 Dec 18.
2
Low bone density and bone metabolism alterations in Duchenne muscular dystrophy: response to calcium and vitamin D treatment.杜氏肌营养不良症的低骨密度和骨代谢改变:钙和维生素 D 治疗的反应。
Osteoporos Int. 2011 Feb;22(2):529-39. doi: 10.1007/s00198-010-1275-5. Epub 2010 May 11.
3
Glucocorticoid corticosteroids for Duchenne muscular dystrophy.用于杜氏肌营养不良症的糖皮质激素皮质类固醇
Cochrane Database Syst Rev. 2008 Jan 23(1):CD003725. doi: 10.1002/14651858.CD003725.pub3.
4
Comparison of titanium elastic nails with traction and a spica cast to treat femoral fractures in children.钛弹性髓内钉与牵引及髋人字石膏治疗儿童股骨骨折的比较
J Bone Joint Surg Am. 2004 Apr;86(4):770-7. doi: 10.2106/00004623-200404000-00015.
5
Fracture prevalence in Duchenne muscular dystrophy.杜氏肌营养不良症中的骨折患病率。
Dev Med Child Neurol. 2002 Oct;44(10):695-8. doi: 10.1017/s0012162201002778.
6
Fracture risk in patients with muscular dystrophy and spinal muscular atrophy.肌营养不良症和脊髓性肌萎缩症患者的骨折风险
J Rehabil Med. 2001 Jul;33(4):150-5.
7
Flexible intramedullary nailing for the treatment of unicameral bone cysts in long bones.弹性髓内钉治疗长骨单房性骨囊肿
J Bone Joint Surg Am. 2000 Oct;82(10):1447-53. doi: 10.2106/00004623-200010000-00011.
8
Bone mineral density and fractures in boys with Duchenne muscular dystrophy.杜兴氏肌营养不良症男孩的骨矿物质密度与骨折情况
J Pediatr Orthop. 2000 Jan-Feb;20(1):71-4.
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Modern trends in internal fixation of femoral shaft fractures in children. A critical review.
J Pediatr Orthop B. 1997 Apr;6(2):117-25. doi: 10.1097/01202412-199704000-00007.
10
Fracture of the femur in the Duchenne muscular dystrophy patient.杜氏肌营养不良症患者的股骨骨折。
J Pediatr Orthop. 1981;1(2):203-7. doi: 10.1097/01241398-198110000-00012.

柔性髓内钉治疗肌病患者的股骨远端骨折

Flexible intramedullary nailing for distal femoral fractures in patients with myopathies.

作者信息

Huber Hanspeter, André Guillaume, Rumeau Francine, Journeau Pierre, Haumont Thierry, Lascombes Pierre

机构信息

Department of Pediatric Orthopaedic Surgery, CHU Brabois Hôpital d'Enfants, Chirurgie Infantile A, Rue du Morvan, 54500 Vandoeuvre les Nancy, France ; Department of Surgery, University Children's Hospital of Zürich, Steinwiesstrasse 75, 8032 Zurich, Switzerland.

出版信息

J Child Orthop. 2012 Jun;6(2):119-23. doi: 10.1007/s11832-012-0399-x. Epub 2012 Apr 11.

DOI:10.1007/s11832-012-0399-x
PMID:23730342
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3364347/
Abstract

PURPOSE

Distal femoral fractures are quite common in nonambulating patients with myopathies, as they present marked osteoporosis. The deterioration of preexisting knee flexion contracture is a known problem, as these fractures are usually angulated posteriorly. The goals of treatment are to reduce immobilization and bed rest to a minimum, prevent function loss, and prevent refracture. The aim of our work was to investigate if these goals can be achieved by an operative treatment with closed reduction and flexible intramedullary nailing (FIN).

METHODS

Six distal femoral fractures in four nonambulating patients with myopathies (three Duchenne muscular dystrophy and one nemaline myopathy) were treated with FIN between 2005 and 2011. Patient charts and radiographs were reviewed to determine if intra- or postoperative complications occurred and to detect the interval to wheelchair mobilization and hospital discharge. Pre- and postoperative knee flexion contracture was noted from the patient charts of our reeducation unit, where patients were already known preoperatively.

RESULTS

Wheelchair mobilization without further immobilization after an interval of 2-3 days was possible. No aggravation of knee flexion contracture was detected in our patient series. No complications associated to the operative treatment itself and no refractures in the follow up occurred.

CONCLUSION

Our experience showed that FIN is a low invasive and sufficiently stable osteosynthesis in such fractures. Left in place, nails will reinforce mechanical stability.

摘要

目的

股骨远端骨折在患有肌病的非行走患者中相当常见,因为他们存在明显的骨质疏松。已知的问题是,由于这些骨折通常向后成角,先前存在的膝关节屈曲挛缩会恶化。治疗的目标是将固定和卧床休息降至最低限度,防止功能丧失,并防止再次骨折。我们研究的目的是调查通过闭合复位和弹性髓内钉固定术(FIN)进行手术治疗是否能够实现这些目标。

方法

2005年至2011年间,对4例患有肌病的非行走患者(3例杜氏肌营养不良症和1例杆状肌病)的6例股骨远端骨折采用FIN进行治疗。回顾患者病历和X光片,以确定是否发生术中或术后并发症,并检测到轮椅活动和出院的间隔时间。术前和术后膝关节屈曲挛缩情况从我们康复治疗单元的患者病历中记录,这些患者术前就已为我们所知。

结果

在间隔2 - 3天后即可进行无需进一步固定的轮椅活动。在我们的患者系列中未检测到膝关节屈曲挛缩加重。未发生与手术治疗本身相关的并发症,随访期间也未出现再次骨折。

结论

我们的经验表明,FIN在这类骨折中是一种低侵入性且稳定性足够的骨固定方法。钉子留在原位将增强机械稳定性。