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[在饲料中使用抗生素期间仔猪和育肥猪治疗强度的计算]

[Calculation of therapeutic intensity for piglets and fattening pigs during the use of antibiotics in feed].

作者信息

Müntener R C, Stebler R, Horisberger U, Althaus R F, Gassner B

机构信息

Institut für Veterinärpharmakologie und -toxikologie der Universität Zürich.

出版信息

Schweiz Arch Tierheilkd. 2013 Jun;155(6):365-72. doi: 10.1024/0036-7281/a000472.

DOI:10.1024/0036-7281/a000472
PMID:23732383
Abstract

Oral treatments for groups of pigs via medicated feed must be prescribed on specific forms submitted to veterinary authorities. We analyzed 869 such prescription forms for the year 2009 representing the treatment of 69'863 piglets and 31'506 fattening pigs. Parameters under investigation were indication and quantity of antimicrobials prescribed. Most of the treatments took place at weaning with 10 - 14 kg and again at the beginning of the fattening period with 20 - 29 kg body weight. The average body weights at treatment were 16 kg (piglets) and 29 kg (fatteners). In analogy with the indicator DID of human medicine, we developed PIDvet describing the prescribed dose per 1000 individuals on given day in veterinary medicine. Calculated PIDvet on a given day was 180.9 for the whole population, 297.6 for piglets and 83.2 for fatteners. This shows PIDvet to be useful to stratify therapeutic intensity in different age classes and could represent a new tool to monitor the use of antibiotics.

摘要

通过加药饲料对猪群进行口服治疗,必须按照提交给兽医当局的特定表格进行处方。我们分析了2009年的869份此类处方表格,这些表格代表了对69863头仔猪和31506头育肥猪的治疗情况。所调查的参数为处方抗菌药物的适应症和数量。大多数治疗在仔猪体重10 - 14千克断奶时进行,以及在育肥期开始时体重20 - 29千克时再次进行。治疗时的平均体重分别为16千克(仔猪)和29千克(育肥猪)。与人类医学的指标DID类似,我们开发了PIDvet,用于描述兽医学中给定日期每1000头动物的规定剂量。给定日期计算出的整群猪的PIDvet为180.9,仔猪为297.6,育肥猪为83.2。这表明PIDvet有助于对不同年龄组的治疗强度进行分层,并且可能成为监测抗生素使用的一种新工具。

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