Br J Psychiatry. 2013 Jun;202:396-7. doi: 10.1192/bjp.bp.112.110650.
Depressive symptoms and depressive illness are associated with impairments in sexual function and satisfaction but the findings of randomised placebo-controlled trials demonstrate that antidepressant drugs can be associated with the development or worsening of sexual dysfunction. Sexual difficulties during antidepressant treatment often resolve as depression lifts but may persist over long periods, and can reduce self-esteem and affect mood and relationships adversely. Sexual dysfunction during antidepressant treatment is typically associated with many possible causes, but the risk of dysfunction varies with differing antidepressants, and should be considered when selecting an antidepressant.
抑郁症状和抑郁障碍与性功能和性满意度受损有关，但随机安慰剂对照试验的结果表明，抗抑郁药可能与性功能障碍的发展或恶化有关。抗抑郁治疗期间的性困难通常随着抑郁的缓解而解决，但可能会持续很长时间，并会降低自尊心，对情绪和人际关系产生不利影响。抗抑郁治疗期间的性功能障碍通常与许多可能的原因有关，但不同抗抑郁药的功能障碍风险不同，在选择抗抑郁药时应加以考虑。
